Heather Markham, PMHNP | Treatment-Resistant Depression Specialist in Colorado

When medications don’t work, you need more than a prescription—you need a provider who truly sees you.

At Axis Integrated Mental Health, that provider is Heather Markham, PMHNP—a board-certified psychiatric nurse practitioner specializing in complex cases like treatment-resistant depression.

From Hospital Floors to Healing Minds

Heather’s journey into psychiatry began far from the therapy office.

She started her career in:

• Emergency rooms

• Cardiac units

• Infectious disease and case management

But no matter the setting, one truth kept showing up:

“Every patient had unmet mental health needs. We just weren’t treating them.”

That realization led Heather to pivot. While earning her Master’s from the University of Colorado, she completed clinical training in:

• Emergency Psychiatry at UCH

• The Functional Neurologic Disorder Clinic

• Telehealth for Alaska Native populations

• Inpatient and outpatient treatment for bipolar, psychosis, and trauma

Why Choose Heather for Treatment-Resistant Depression?

1. She Sees the Full Picture

Heather connects the dots between body, mind, and environment. She doesn’t treat diagnoses in isolation.

“Mental health isn’t a silo—it’s part of everything.”

2. She Challenges Flawed Research Gaps

Heather is evidence-based—but not blindly. She questions studies that exclude those most in need:

“If your research leaves out people with bipolar, psychosis, or addiction—that’s not science. That’s system failure.”

3. She Makes Lifestyle a Key Part of Treatment

Sleep, nutrition, and movement aren’t afterthoughts—they’re part of the plan. Heather helps patients build practical routines to support long-term recovery.

Heather’s Mental Health Toolkit

Heather doesn’t just treat symptoms—she builds resilience. Her personal toolkit includes:

• Daily endurance training (yes, she races in triathlons!)

• “Permission to Feel” tools for emotional awareness

• Audible & Boundless for continuous growth

• Harp music and humor as healing tools

• Her go-to mantra: “I can do hard things.”

Conditions Heather Treats

Heather specializes in integrated care for:

• Depression and anxiety

• Treatment-resistant depression

• Bipolar disorder and psychosis

• Trauma and emotional dysregulation

• Co-occurring substance use

Where Heather Sees Patients

You can find Heather primarily in Westminster, or you can see her for a telehealth visist at any Axis Integrated Mental Health clinic in:

• Aurora, CO

• Westminster, CO

• Louisville, CO

What Patients Are Saying

“Heather is real. She listens and actually teaches you about your own brain. She made me feel like I wasn’t broken—I just hadn’t had the right help.”

“Endurance sports taught me how to be uncomfortable for long stretches. That’s what therapy asks of people, too. Heather gets that—and she’s not afraid to sit with you through it.”

Need Help When Meds Haven’t Worked?

If you’ve tried two or more antidepressants and still feel stuck, you’re not alone. Treatment-resistant depression is real—but so is recovery.

Heather Markham, PMHNP is here to help.

Colorado currently ranks #50 of all states for the prevalence of mental illness and #47 for adults with suicidal ideation. Book an appointment before she fills up.

Frequently Asked Questions

Is Heather Markham board-certified?
What advanced treatments are available for treatment-resistant depression?
Can I get Spravato or ketamine therapy at Axis?
Does Axis accept insurance for these treatments?
Is telehealth available for psychiatric care in Colorado?

Is Axis Integrated Mental Health accepting new patients?